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XBIRA 250MG TABLET (CIPLA)- Abiraterone acetate |Apple pharmaceuticals

XBIRA 250MG

          Abiraterone is sold under brand name Xbira 250mg, the main ingredient which is used as abiraterone . Xbira 250mg is belongs to type of anti-cancer medicationthat will act by decline the androgen production in the body. Androgen is a male hormone that canmaintance the tumor cell in prostate glands. Actually thisdrug is given by co administration with prednisolone, a steroid which reduce the liability of side effects produced by Abiraterone.

DOSAGE

         The prescribed dose of Xbira 250mg is initial as 4 tablets given orally once daily. The drug Xbira administrated combinationwith 5mg prednisolone twice daily in empty stomach. Xbira 250mg Tablets given on an empty stomach. Foodshould not be taken for at least 2 hours before and at least 1 hour after the dose of Xbira Tablets is taken. Swallowedwhole with water. Chew the tablets or Do not crush

MECHANISM OF ACTION

         Androgens are balancethe production of malignant in prostate. Xbira 250mg(abiraterone acetate) is belongs to anti androgen drugs, thatcauses to suppress the enzyme 17α-hydroxylase C 17, 20-lyase (CYP17), it is involves in androgen conglomerate. Reduce the serum testosterone level. Declined the tumor cell occurred.

PHARMACOKINETICS

Absorption:  Time to maximum plasma concentration of Xbira 250mg tablet takes 12 hours.
Distribution: Maximum bound to the human plasma protein like albumin and alpha-1 acid                                         glycoprotein.
Metabolism: Themain two metabolites of Abiraterone in human plasma are Abiraterone sulphate and                       N-oxide Abiraterone sulphate.
Excretion:    The drug mainly excreted in 88% feces and 5% in urine Half-life of tablet Xbira is 12 ±                      5 hours.

xbira 250mg
xbira 250mg

MISSED DOSE

           If patient missed the dose of Xbira 250mg, that missed dose will be skipped and follow the regular dosing schedule.

OVERDOSAGE

           Xbira 250mg has no essential antidote, If overdose occurs end treatment with the drug and give general supportive measures such as monitoring arrhythmias and cardiac failure and assess liver function.

DRUG INTERACTION

           Interaction of Xbira 250mg with dextromethorphan will raises the Cmax and AUC of dextromethorphan Interaction Xbira 250mg with strong CYP3A inhibitors or inducers , concomitant use with caution because pharmacokinetics is not evaluated.

xbira 250mg tablet
xbira 250mg tablet

SIDE EFFECTS

Common effects :

         Fatigue, Arthralgia, Hypertension, Nausea, edema, Hypokalemia, Diarrhea, vomiting, Cough, headache, Glucocorticoid deficiency,Mineral corticoid deficiency, Hepatotoxicity, Hypertension, Decrease in ka level, Adrenocortical insufficiency Musculo skeletal and Connective tissue.

disorders:                 Joint swelling, discomfort, muscle discomfort General Disorder:Oedema
Cardiac disorders:    Hot flush, hypertension, arrhythmias, chest pain, cardiac failure
GIT disorders:          Diarrhea, dyspepsia Infections and Infestation:UTI
Pulmonary disorder: Cough
Renal:                        Urinary frequency, nocturia
Injuries:                     Fractures

STORAGE

          The drug stored at 15℃-30℃ Keep the drug in dry place.


Phone Number

+91-9987711567

URL


Email ID

  applepharmaceutical@gmail.com
  info@myapplepharma.com
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