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Zytiga 250mg tablet: Abiraterone Price & Side effects | Mypplepharma

Zytiga 250mg

         Abiraterone is sold under brand name Zytiga Zytiga is belongs to type of anti-cancer medication that will act by decline the androgen production in the body. Androgen is a male hormone that canmaintance the tumor cell in prostate glands. Actually this drug is given by co administration with prednisolone, a steroid which reduce the liability of side effects produced by Abiraterone.

DOSAGE

         The prescribed dose of Zytiga is initial as 4 tablets given orally once daily. The drug Zytiga administrated combination with 5mg prednisolone twice daily in empty stomach. Zytiga Tablets given on an empty stomach. Food should not be taken for at least 2 hours before and at least 1 hour after the dose of Zytiga Tablets is taken. Swallowed whole with water.
Chew the tablets or Do not crush

MECHANISM OF ACTION

          Androgens are balance the production of malignant in prostate. Zytigais belongs to anti androgen drugs, that causes to suppress the enzyme 17α-hydroxylase C 17, 20-lyase (CYP17), it is involves in androgen conglomerate. Reduce the serum testosterone level. Declined the tumor cell occurred.

PHARMACOKINETICS

Absorption:   Time to maximum plasma concentration of Zytiga tablet takes 12 hours.
Distribution:  Maximum bound to the human plasma protein like albumin and alpha-1 acid                                         glycoprotein.
Metabolism:  The main two metabolites of Abiraterone in human plasma are Abiraterone sulphate                             and N-oxide Abiraterone sulphate.
Excretion:      The drug mainly excreted in 88% feces and 5% in urine
                     Half-life of tablet Zytiga is 12 ± 5 hours.
zytiga 250mg
zytiga 250mg

SAFETY AND WARNING

       Any allergy, serious liver problem or pregnant in patient, Zytiga therapy should be stopped
Avoid taking of other medications, i.e prescription, over-the-counter, vitamins, herbal remedies, etc be sure to inform the doctors before the treatment. Do not take Aspirin administrated and products containing aspirin till doctor particularly allow the drug. 

OVERDOSAGE:

        Zytiga has no essential antidote, If overdose occurs end treatment with the drug and give general supportive measures such as monitoring arrhythmias and cardiac failure and assess liver function

DRUG INTERACTION

        Interaction of Zytiga with dextromethorphan will raises the Cmax and AUC of dextromethorphan Interaction Zytiga with strong CYP3A inhibitors or inducers , concomitant use with caution because pharmacokinetics is not evaluated.

STORAGE

        The drug stored at 15℃ - 30℃  Keep the drug in dry place.

MISSED DOSE

         If patient missed the dose of Zytiga, that missed dose will be skipped and follow the regular dosing schedule.

zytiga 250mg tablet
zytiga 250mg tablet

SIDE EFFECTS

Common effects :
Fatigue, Arthralgia, Hypertension, Nausea, edema, Hypokalemia, Diarrhea, vomiting, Cough, headache, Glucocorticoid deficiency, Mineral corticoid deficiency, Hepatotoxicity, Hypertension, Decrease in ka level, Adrenocortical insufficiency
Musculo skeletal and Connective tissue disorders:Joint swelling, discomfort, muscle discomfort
General Disorder: Oedema
Cardiac disorders: Hot flush, hypertension, arrhythmias, chest pain, cardiac failure
GIT disorders: Diarrhea, dyspepsia
Infections and Infestation:UTI
Pulmonary disorder: Cough
Renal:Urinary frequency, nocturia
Injuries: Fractures.

Phone Number

+91-9987711567

URL

https://myapplepharma.com/abiraterone-250mg.php

Email IDapplepharmaceutical@gmail.com

info@myapplepharma.com

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